Program
Wednesday, November 9th
11:30h Depart from Atocha
13:00-14:00h Check in and poster set-up
14:00-15:30h Lunch
15:30-16:30h Welcome and Keynote Lecture
Key players ATG9A and ATG2A in initiation of autophagosome formation
Dr. Sharon Tooze
Francis Crick Institute, London, UK
16:30-17:30h Session 1
Chair: Guillermo Velasco
“Physiological Roles of Autophagy”
16:30-16:50h Role of autophagy during cell competition in heart development and regeneration
Lorena Esteban Martínez
Lorena Esteban Martínez
16:50-17:10h An alternative metabolic link connects glutamine and autophagy to control glutamoptosis
Mercedes Tomé Montesinos
Mercedes Tomé Montesinos
17:10-17:30h Post-ER degradation of misfolded GPI-anchored proteins is linked with microautophagy
Leticia Lemus
Leticia Lemus
17:30-18:00h Coffee Break
18:00-19:00h Session 2
Chair: Nadezda Apostolova
“Physiological Roles of Autophagy”
18:00-18:20h Functional differences in microglial and neuronal macroautophagy under proteotoxic stress
Diego Ruano Caballero
Diego Ruano Caballero
18:20-18:40h cAMP-Protein Kinase A and Stress-Activated MAP signaling mediate transcriptional control of autophagy in fission yeast during glucose limitation or starvation
Armando Pérez Díaz
Armando Pérez Díaz
18:40-19:00 h Finding Nemo: discovering novel autophagy modulators with zebrafish
Adrian Santos Ledo
Adrian Santos Ledo
19:00-20:30h SEFAGIA General Assembly
20:30-22:00h Dinner at hotel
Thursday, November 10th
8:00h Breakfast
9:00-10:00h Keynote Lecture
Dr. Felix Randow
How cells deploy autophagy to protect aganist bacterial invasion
MRC Laboratory of Molecular Biology, Cambridge, UK
MRC Laboratory of Molecular Biology, Cambridge, UK
10:00-11:00h Session 3
Chair: Raúl Durán
“Physiological Roles of Autophagy”
10:00-10:20h Photosynthetic assimilation of CO2 regulates TOR activity
Manuel Jesús Mallén Ponce
“Autophagy and Disease”
10:20-10:40h Role of autophagy in the hepatoprotective role of the antiretroviral drug Rilpivirine: when less is more
Nadezda Apostolova
10:40-11:00h Selective autophagy plays a protective role against acute and age-related retinal degeneration
Juan Ignacio Jiménez Loygorri
11:00-11:15h Group photo
11:15-12:30h Coffee break and posters (even ID numbers)
12:30-12:40h Agilent “Seahorse XF as a tool for mitophagy dysfunction and mitochondrial quality”
Alfredo Caro-Maldonado
Seahorse Product Specialist at Agilent Technologies
Seahorse Product Specialist at Agilent Technologies
12:40-13:40h Session 4
Chair: José Manuel Fuentes
“Autophagy and Disease”
12:40-13:00h Characterization of the molecular mechanism of autophagy inhibition by HER2
Jetsy Karina Montero Vergara
13:00-13:20h Dysregulation of the autophagic-lysosomal pathway in Parkinson’s disease associated to GBA
Eddie Pradas Gracía
13:20-13:40h Does AMBRA-1 play onco-suppressive functions in skin squamous cell carcinomas?
Estibaliz Gabicagogeascoa Corta
14:00-15:30h Lunch
15:30-17:00h Session 5
Chair: Patricia Boya
"Junior PI Symposium and WIA Presentation"
15:30-15:50h Microvascular endothelial cell autophagy regulates neutrophil trafficking in inflammation
Natalia Reglero Real
15:50-16:10h Control of mitosis by lysosomes to develop CIN-targeting cancer therapy
Caroline Mauvezin
16:10-16:30h Anacardium occidentale extract promotes autophagy and protects against glycative stress derived cytotoxicity
Eloy Bejarano Fernández
16:30-16:50h A mammalian target of rapamycin-perilipin3 (mTORC1-Plin3) pathway is essential to activate lipophagy and protects against hepatosteatosis
Marina García Macia
16:50-17:00 WIA presentation
Marina García
17:00-18:15h Coffee Break and posters (odd ID numbers)
18:15-19:15h Session 6
Chair: Ricardo Escalante
“Autophagy and Disease”
18:15-18:35h Differential process of mitophagy in neurons and astrocytes associated to Parkinson’s disease related to a-synuclein
Isabel Lastres Becker
18:35-18:55h Deciphering the formation and clearance of glycogen aggregates in Lafora disease
Jordi Durán Castells
18:55-19:15 Targeting autophagy vulnerabilities for cancer treatment
Silvia Vega-Rubin-de-Celis
19:30h Depart from the hotel
19:45 -20:45h Guided Tour
20:55 -22:15h Dinner on your own in downtown Toledo
22:30h Toledo Depart to hotel
Friday, November 11th
8:00h Breakfast
9:00-10:00h Keynote Lecture
Of cyclers and proteostasis, the secret life of Ambra1
Dr. Francesco Cecconi
University of Rome Tor Vergata, Rome, Italy and Danish Cancer Research Center, Copenhagen, Denmark
Dr. Francesco Cecconi
University of Rome Tor Vergata, Rome, Italy and Danish Cancer Research Center, Copenhagen, Denmark
10:00-11:20h Session 7
Chair: José Luis Crespo
“Autophagy and Disease”
10:00-10:20h Astrocyte-derived small extracellular vesicles exert a protective effect on euron and astrocytes primary cultures damaged with epoxomicin
Jesús Alarcón Gil
Jesús Alarcón Gil
10:20-10:40h Diabetes type 3: role of human amylin and therapeutic approaches
Carlos González-Blanco
Carlos González-Blanco
“Mechanisms of Autophagy”
10:40-11:00h Molecular mechanisms of the interaction between the PROPPIN Atg21 and Atg16
Miranda Bueno Arribas
Miranda Bueno Arribas
11:00-11:20h TP53INP2 regulates selective autophagy
Saška Ivanova
Saška Ivanova
11:20-12:20h Coffee break and posters
12:20-13:40h Session 8
Chair: Marta Martínez
“Mechanisms of Autophagy”
12:20-12:40h H2S regulates selective ER-phagy and mitophagy through persulfidation
Angeles Aroca
Angeles Aroca
“Chaperone-Mediated Autophagy”
12:40-13:00h Chaperone-mediated autophagy controls proteomic and transcriptomic pathways to maintain glioma stem cell activity
Ander Matheu Fernández
Ander Matheu Fernández
13:00-13:20h Role of pericytes´ chaperone-mediated autophagy in tissue repair after injury/inflammatory damage
María Dolores Salinas Hidalgo
María Dolores Salinas Hidalgo
13:20-13:40h Dissecting the regulation of CMA in a natural model of impaired glucose homeostasis, the rainbow trout
Emilio José Vélez Velázquez
Emilio José Vélez Velázquez
13:40-13:50h Concluding remarks
14:00-15:30h Lunch
16:00h Depart to Atocha Station